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Leukodystrophies are genetic disorders primarily affecting the white matter of the central nervous system (ie. the brain or spinal cord). Leukodystrophies may also be referred to as Inherited (or genetic) White Matter Disorders (IWMDs) meaning that the affected person has been born with a genetic abnormality that causes the disease. There are over 100 identified leukodystrophies, with some so rare they are yet to be named. Leukodystrophy affects males and females of all ages and ethnic backgrounds, most notably children.

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