Reproductive options

PGT (Pre-implantation genetic testing) is available to couples that are at risk of having a child with a specific genetic or chromosome disorder. It prevents the birth of an affected child by testing an embryo before it is implanted in the uterus (womb).

Briefly, it involves the use of Assisted Reproductive Technology (ART), which in other circumstances is offered to couples with fertility problems. The aim is to obtain and fertilise a number of eggs. Once fertilised, the embryos develop for three days and then one cell is removed from each embryo. The genetic material (DNA or chromosomes) within each cell is then tested for the altered gene or chromosome abnormality. Up to two unaffected embryos are then transferred to the uterus with the hope that they will implant and form a pregnancy. If successful, a pregnancy should be unaffected. PGT is a lengthy and complex process. More information about PGT treatment can be found here.

Is it available for my condition?

The official list of conditions approved for PGT within the UK can be found at the Human Fertilisation and Embryology Authority.

If you do not see your condition on the list, you can ask your genetic counsellor for advice on how to apply to get your condition approved.

For further information on how to be referred please visit Guys and St Thomas hospital. There are also satellite clinics at the following hospitals.

For parents facing difficult decisions around pregnancy, the organisation Antenatal Results and Choices (ARC) provides excellent information and support resources.